围绝经期女性睡眠障碍的研究进展

Research progresses of sleep disorder in perimenopausal women

睡眠障碍是围绝经期女性的常见症状之一,主要表现为入睡困难、夜间觉醒次数增多、晨间早醒、醒后无法再入睡等,其原因可能与该时期出现的雌激素水平变化及其变化所导致的血管舒缩症状、情绪障碍等有关。绝经相关的睡眠障碍发生率受人种、遗传因素、环境因素以及患慢性疾病和药物治疗等情况的影响差异较大。绝经睡眠障碍治疗包括一般治疗和药物治疗,其中激素替代治疗有一定的疗效。该文就围绝经期女性睡眠障碍的流行病学研究、诱导因素及干预治疗进展等进行综述。

Sleep disorder is one of common symptoms in perimenopausal women with major manifestations of difficulty sleeping, frequently waking up at night, early morning waking up, and unable to fall asleep after waking up, which may be related to oestrogen level changes in this period and resulting in vasomotor symptoms and mood disorders. The incidence of sleep disorder related to menopause is gready affected by race, genetic factors, environmental factors, chronic diseases, and medications, etc. The treatments of menopausal sleep disorder include general therapy and medications. The hormone replacement therapy has certain efficacy. This article reviews progresses of epidemiological studies, inducing factors, and intervention treatments of sleep disorder in perimenopausal women.