阻塞性睡眠呼吸暂停综合征与2型糖尿病关系的研究进展

Obstructive Sleep apnea Syndrome and the Research Progress of Relationship Between Type 2 Diabetes mellitus

目的探究阻塞性睡眠呼吸暂停综合征(OSAS)与2型糖尿病的关系。方法选取2013年3月—2016年3月该院60例OSAS患者作为实验组,将这60例OSAS患者按照病情的严重程度分为A组(轻度)、B组(中度)、C组(重度),同时选取60例健康人员作为对照组,对比各组受检者之间的血糖水平。结果实验组空腹血糖值(6.83±2.17)mmol/L、胰岛素水平(25.36±7.52)m U/L以及餐后2 h血糖水平(25.36±7.52)mmol/L、胰岛素水平(78.52±12.31)m U/L均与对照组差异显著(P<0.05)。同时A、B、C 3组之间的血糖水平以及胰岛素水平也存在显著差异(P<0.05)。结论 OSAS会导致患者出现糖代谢异常的情况,增加患者2型糖尿病的发病几率。

Objective To explore the obstructive sleep apnea syndrome （OSAS） with type 2 diabetes. Methods Selection in March 2013 to March 2016, 60 patients with OSAS patients as experimental group, the 60 patients with OSAS were accord-ing to the severity of the illness were divided into group A （slight） and group B （medium）, group C （heavy）, and 60 cases of healthy persons as control group, compared between each client＆#39;s blood sugar level. Results The experimental group fasting glucose values （6.83±2.17） tendency for L, insulin levels （25.36±7.52） mU/L and postprandial 2 hours blood glucose levels （25.36±7.52） tendency for L, insulin levels （78.52±12.31） mU/L are significant difference with control group （P〈 0.05）. At the same time, A, B, C three groups between blood glucose and insulin levels there are significant differences（P〈0.05）. Conclusion OSAS may lead to more than sugar metabolism patients, increase the risk of type 2 diabetes mellitus patients.