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血清YKL-40与急性出血性脑卒中相关分析 被引量:2

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摘要 目的观察脑出血患者血清人类软骨糖蛋白39(YKL-40)水平与脑出血量及神经功能损伤的相关性。方法选择脑出血患者100例作为实验组,另选择同期门诊健康体检者50例作为对照组,分别检测患者第1、3、7和14天血清YKL-40水平。结果实验组患者YKL-40水平明显高于对照组[(431.5±120.8)ug/L vs(80.5±53.2)ug/L,P<0.001];小量出血、中量出血、大量出血患者的血清YKL-40水平均在7d内逐渐升高,且第7天达到最大值,随后逐渐下降(P<0.05);重度神经损伤患者的血清YKL-40水平明显高于中度、轻度损伤患者(P<0.05)。结论脑出血患者的血清YKL-40水平与患者的脑出血量及神经功能损伤程度存在相关性,可为脑出血患者临床诊疗提供依据。
出处 《贵州医药》 CAS 2016年第6期600-602,共3页 Guizhou Medical Journal
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