中年人群体育锻炼与血脂水平关系的横断面研究

A Cross-sectional Study for the Relationship Between Exercise and Serum Lipid Level in Middle-aged Population

目的：了解我国中年人群体育锻炼（Exercise）与血脂水平的关系。方法：利用中国心血管流行病学多中心协作研究数据,选择北京、广州城乡人群3 482人,年龄35~59岁。分性别将体育锻炼情况分为3组,即无锻炼组、体育锻炼日均耗能（EEexer）中位数以下组即锻炼较少组和中位数以上组即锻炼较多组。采用调查问卷法收集平时体育锻炼的种类及持续时间,计算平时每日体育锻炼能量消耗（EEexer）。利用协方差分析评估体育锻炼能耗与血脂水平的关系。结果：在男、女性人群中,分别有47.1%（807/1712）和41.1%（727/1770）有体育锻炼。在控制年龄、城乡、受教育水平、吸烟、饮酒、体重指数及除体育锻炼以外的体力活动水平（EEPA）后,女性总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、非高密度脂蛋白胆固醇（non-HDL-C）、甘油三酯（TG）随活动分组增高呈降低趋势,其中LDL-C及non-HDL-C水平组间差异有统计学意义（P2.62（MET·h）/d以上组LDL-C及non-HDL-C水平降低约0.14 mmol/L（P=0.0063）、0.14 mmol/L（P=0.0155）;男性中在调整上述因素后,TC、LDL-C、non-HDL-C、TG随着分组水平增高而呈降低的趋势,但差异无统计学意义。高密度脂蛋白胆固醇（HDL-C）在男/女性中,组间差别均无统计学意义。结论：研究显示社区女性中年人群中体育锻炼能耗较高组LDL-C、non-HDL-C水平显著低于无体育锻炼组,该作用独立于工作中及其他体力活动。

Objective： To investigate the relationship between exercise and serum lipid level in middle-aged population.Methods： Based on ＂multicenter collaborative study of cardiovascular epidemiology＂ research, a total of 3482 subjects at the age of（35-59） years from urban and rural areas of Beijing and Guangzhou were enrolled in this study. According to daily energy expenditure of exercise（EEexer）, the participants were divided into 3 groups： No exercise group,（daily） EEexer below median group and（daily） EEexer above median group. The type and duration of exercise were collected by the questionnaire, daily EEexer was calculated and the relationship between exercise and serum lipid level was estimated by covariance analysis.Results： There were 47.1%（807/1712） male and 41.1%（727/1770） female participants having exercise. With controlledage, area, education level, smoking, drinking, BMI and energy expenditure of physical activity outside of exercise（EEPA）, serum levels of TC, LDL-C, non-HDL-C and TG were decreased in women by elevated EEexer groups accordingly, and among them, there were significant differences in LDL-C and non-HDL-C levels between groups, P0.05; compared with No exercise group, in female daily EEexer above median group, LDL-C and non-HDL-C levels decreased about 0.14 mmol/L, P=0.0063 and 0.14 mmol/L, P=0.0155 respectively; while in men, TC, LDL-C, non-HDL-C and TG levels showed a decreasing trends by elevated EEexer groups but with no statistical significance. No association was found for HDL-C in men and women.Conclusion： Serum levels of LDL-C and non-HDL-C were lower in female daily EEexer above median group than No excise group, the effects were independent from working and other physical activities.