过表达P53基因对人成骨肉瘤细胞Saos-2凋亡的影响
摘要
骨肉瘤（osteosarcoma）是青少年中最常见的恶性骨肿瘤之一,该肿瘤好发于儿童胫骨的上段和股骨的下段且恶性程度极高,预后不良。进些年来,多种药物的联合化疗以及手术治疗使骨肉瘤患者的5年生存率由原来的20%提高到70%左右。然而进30年来,5年生存率波动幅度较大,部分患者手术后复发率高,对于出现远处转移的患者5年生存率不到30%。
出处
《中国药物与临床》
CAS
2016年第7期966-968,I0002,共4页
Chinese Remedies & Clinics
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