膝关节置换术结合中药疗法对膝关节骨性关节炎的临床疗效研究

Clinical efficacy of knee arthroplasty combined with traditional Chinese medicine on knee osteoarthritis

目的探讨膝关节置换术结合中药疗法对膝关节骨性关节炎治疗的临床疗效,为以中西医结合指导下开展的膝关节骨性关节炎相关疗法提供依据。方法选择纳入我院2012年1月至2014年12月的膝关节骨性关节炎患者40例,随机分为两组,其中阳性对照组20例,采用膝关节置换术治疗,观察组20例,采用膝关节置换术结合中药疗法治疗,经过4周的治疗后,通过临床症状评估、Rasmussen分级及临床疗效统计以评估治疗的效果。结果两组患者治疗前的一般资料、症状积分和Rasmussen分级评分,差异均无显著统计学意义(P<0.05);治疗后两组患者的症状积分比较,差异具有统计学意义(P<0.05),两组病例治疗后临床症状及体征各指标评分组间比较观察组与对照组治疗后比较,除生活及工作能力、膝、跟腱反射治疗后评分无统计学差异(P>0.05),其余项目差异均具有统计学意义(P<0.05);治疗后两组患者的症状积分和Rasmussen分级评分比较,差异具有显著统计学意义(P<0.05);单纯膝关节置换术的总有效率达60.0%,膝关节置换术结合中药疗法观察组的总有效率达95.0%。结论膝关节置换术结合中药疗法治疗及单纯膝关节置换术对膝关节骨性关节炎患者具有一定的治疗效果,可以改善膝关节骨性关节炎患者的临床症状,膝关节置换术结合中药疗法治疗效果更佳。

Obje ctive To investigate the clinical efficacy of knee arthroplasty combined with Chinese herb on the treatment of osteoarthritis of the knee,and to provide the basis of integrative medicine under the guidance of knee arthritis therapy. Me thods Forty patients with osteoarthritis of the knee in our hospital from January 2012 to December 2014 were selected. They were randomly divided into two groups,20 patients in the positive control group with knee replacement surgery and 20 patients in the observation group with knee arthroplasty combined with traditional Chinese medicine. After 4 weeks of treatment,clinical symptom assessment,Rasmussen grade,and clinical efficacy of statistics were evaluated. Re sults The general information,symptom score,and Rasmussen grading were not statistically significant between the two groups before the treatment（ P〈0. 05）. The symptom scores between the two groups was statistically different after the treatment（ P〈0. 05）. Except the ability to live and work and the reflection of the knee and angle,clinical symptoms and signs between the two groups were not significantly different（ P〉0. 05）after the treatment. The remaining items were statistically different（ P〈0. 05）. The symptom scores and Rasmussen grading were statistically different after the treatment（ P〈0. 05）. The efficacy of total knee arthroplasty alone was 60. 0%,and it was 95. 0%using the total knee arthroplasty combined with traditional Chinese medicine treatment. Conclusion Knee arthroplasty combined with traditional Chinese medicine has a therapeutic effect. It relieves clinical symptoms in patients with osteoarthritis of the knee with better efficacy.