高血压合并冠心病患者升主动脉弹性功能与不同冠脉病变的相关性分析

Analysis of Correlation between Aortic Elasticity of Patients with Coronary Artery and Hypertension and Coronary Artery Lesions

目的：分析高血压合并冠心病患者升主动脉弹性功能与不同冠脉病变的相关性,并探究其临床适用性。方法：选择从2012年4月~2014年9月于某院接受治疗的90例高血压合并冠心病患者作为研究病例,所有患者入院后均进行检测评价主动脉弹性及冠脉病变程度等,根据病变程度的不同,分为单支病变组、双支病变组及三支病变组3组。观察3组患者僵硬度、冠脉病变评分、升主动脉扩张性情况,并比较升主动脉前壁A、S、E波速度及动脉弹性参数。结果：三支病变组患者的僵硬度、冠脉病变评分、升主动脉扩张性均显著优于单支病变组及双支病变组,差异均具有统计学意义（P〈0.05）;双支病变组患者的僵硬度、冠脉病变评分、升主动脉扩张性均显著优于单支病变组（P〈0.05）;3组患者的升主动脉前壁A波及E波速度基本相符（P〉0.05）;三支病变组患者的升主动脉前壁S波速度显著优于双支病变组及单支病变组,差异具有统计学意义（P〈0.05）,双支病变组患者的升主动脉前壁S波速度显著优于单支病变组,两组比较,差异明显（P〈0.05）;3组患者的舒张压（DBP）、收缩压（SBP）、上肢动脉血压（AP）、平均动脉压（MAP）均基本相符（P〉0.05）;3组患者的动态血压的脉压（PP）比较,差异具有统计学意义（P〈0.05）。结论：高血压合并冠心病患者升主动脉弹性功能降低与冠脉病变程度具有较为密切的关系,可以作为检测心血管的重要因子,适合临床长期推广应用。

Objective：To investigate the correlation between aortic elasticity of patients with coronary artery and hypertension and Coronary artery lesions,and to explore its clinical applicability.Methods：90cases of patients with hypertension and coronary heart disease treated in our hospital from April 2012 to September2014were taken as a research objects,who were examined in aortic elasticity and severity of coronary artery disease,and divided into single vessel lesion group,double vessel lesion group and three branch lesions group three groups according to the severity of coronary artery disease.Then observe the stiffness,coronary lesion score,ascending aortic distensibility of the three groups;and then compare the A,S,E wave velocity of ascending aorta anterior wall and artery elastic parameters.Results：The stiffness,coronary lesion score,ascending aortic distensibility of the three branch lesions group were significantly better than those of single vessel group and double vessel disease group,and the differences were statistically significant（P0.05）;The stiffness,coronary lesion score,ascending aortic distensibility of the double vessel lesion group were significantly better than those of single vessel group（P0.05）;anterior wall of ascending aorta of A wave and E wave velocity of the three groups were nearly consistent（P 0.05）;anterior wall of ascending aorta S wave velocity of the three branch lesions group were significantly better than that of single vessel group and double vessel disease group,and the differences were statistically significant（P0.05）,anterior wall of ascending aorta S wave velocity of the double vessel lesion group were significantly better than that of single vessel group（P0.05）;the diastolic blood pressure（DBP）,systolic blood pressure（SBP）,upper extremity arterial blood pressure（AP）,moving average Pulse pressure（MAP）of the three groups were basically consistent（P0.05）;the ambulatory blood pressure pulse pressure（PP）of the three groups and the difference was statistically significant（P0.05）.Conclusion：The aortic elasticity of patients with coronary artery and hypertension and Coronary artery lesions have close correlation.It can be used as an important factor to detect cardiovascular disease,which is suitable for clinical application.