妊娠早期龈沟液白介素-6及血清雌二醇水平与慢性牙周炎的关系

Relationship between Gingival Crevicular Fluid Interleukin-6 and the Serum Estradiol Levels in Early Pregnancy and Periodontitis

目的:探讨妊娠早期龈沟液IL-6及血清E2水平与慢性牙周炎的关系。方法:在妊娠早期妇女中选取35例牙周健康者(健康组)和55例慢性中、重度牙周炎患者(慢性牙周炎组),分别检查和记录各项牙周临床指数,采集检测并比较两组受试者GCF IL-6及血清E2含量。结果:慢性牙周炎组GCF IL-6含量与PPD、CAL、GI有显著相关性(P<0.05),血清E2含量与其无相关性(P>0.05)。结论:妊娠早期GCF中IL-6水平可以反映牙周炎严重程度,血清E2水平可能不是危险因素。

Objective：To investigate the relationship between Gingival crevicular fluid interleukin-6and the serum estradiol levels in early pregnancy and periodontitis.Methods：35cases of periodontitis（dental clinical periodontal health group）and 55 cases of chronic,severe periodontitis group（chronic periodontitis with teeth）were selected from pregnancy women,who were examined and whose teeth clinical indexes were recorded.Then collect and observe tooth GCF samples IL-6and serum E2 of the two groups.Results：In the chronic periodontitis with teeth group,there is a close relation between the contents of IL-6chronic periodontitis with teeth with PPD,CAL,GI（P0.05）,with no correlation with serum E2levels（P0.05）.Conclusion：In the early pregnancy,GCF IL-6level can reflect the severity of periodontitis,and serum E2 levels may not be a risk factor.