中西医结合治疗晚期中央型非小细胞肺癌疗效观察

Observation of Therapeutic Effect on Advanced Central Non-small Cell Lung Cancer Treated by Combination of TCM and Western Medicine

目的:观察中西医结合治疗晚期中央型非小细胞肺癌的临床疗效。方法:64例随机分为治疗组和对照组各32例。两组均采用西医常规姑息治疗,治疗组加用中药雾化吸入与中药内服治疗。结果:治疗组肿瘤控制临床受益率、体力指数评分、1年生存率均比对照组高(P<0.05),肺癌证候改善更好(P<0.05),2年生存率无统计学差异。结论:中药雾化吸入及内服辅助治疗晚期中央型非小细胞肺癌疗效优于单纯姑息治疗。

Objective：To observe the clinical therapeutic effect of combination of TCM and western medicine in the treatment of advanced central type non-small-cell lung cancer（NSCLC）.Method：64 cases were evenly divided into two groups in random. 32 patients in the treatment group were treated with atomization inhaled decoction combined with formula plus conventional palliative treatment while the other 32 patients in the control group were treated with palliative therapy only. Result：There were more significant improvement of the treatment group in clinical benefit response of cancer control,lung cancer syndrome,physical index score and one year survival rate than that of the control group（P〈0.05）.Conclusion：The therapeutic effect of combination of Chinese herbs by atomization inhaled and by oral administration adjuvant treatment is superior to that of only palliative therapy in the treatment of advanced central type NSCLC.