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多种信号通路在类风湿关节炎发病机制中的研究进展 被引量:10

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摘要 RA是一种全身性的自身免疫病,以慢性滑膜炎症和侵蚀性关节炎为临床特征,可导致关节畸形,最终导致不同程度的残疾。由于RA确切的病因学及发病机制仍未明了,而且信号通路的研究一直是疾病研究的热点方向,它是认清疾病发生发展的关键步骤,为临床疾病的诊断、治疗提供依据,同时能为药物的开发特别是为新型生物制剂提供更安全、更特异的靶点。
出处 《中华风湿病学杂志》 CAS CSCD 北大核心 2016年第7期498-500,共3页 Chinese Journal of Rheumatology
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