大黄保留灌肠治疗急性大面积脑梗死伴意识障碍的临床疗效观察

The curative effect of rhubarb retention enema on acute massive cerebral infarction combined with disturbance of consciousness

目的探讨大黄保留灌肠治疗急性大面积脑梗死伴意识障碍的临床疗效。方法发病24 h内,头颅CT或MRI确诊大面积脑梗死60例,按随机数字表法分为治疗组和对照组各30例。对照组治疗遵循《中国脑血管病防治指南》原则,予西医常规治疗;治疗组在西医常规治疗基础上加用中药生大黄60 g煎水灌肠,隔日1次,14 d后统计疗效。结果治疗组显效21例,有效8例,无效1例,对照组显效10例,有效11例,无效9例,治疗组疗效优于对照组(Z=2.117,P<0.05)。结论急性大面积脑梗死伴意识障碍在常规治疗基础上予以大黄保留灌肠治疗,效果确切,值得在临床上推广应用。

Objective To observe the clinical efficiency of rhubarb retention enema on acute cerebral infarction combined with disturbance of consciousness. Methods Acute massive cerebral infarction was diagnosed by CT or MRI in 60 patients with disturbance of consciousness within 24 hours of onset,and the patients were randomly divided into two groups. The control group（ n = 30） received the conventional medical management of western medicine. The experimental group（ n = 30） was treated with rhubarb retention enema 60 g once every two days for 14 days based on the treatment in the control group. Results The efficiency of the experimental group was significantly higher than that of the control group（ P〈0. 05）. Conclusion Rhubarb retention enema combined with the conventional medical management of western medicine is effective for the patients with acute cerebral infarction combined with disturbance of consciousness.