糖化血红蛋白与冠状动脉病变严重程度的相关性分析

Analysis of the Correlation between Glycosylated Hemoglobin and Severity of Coronary Artery Disease

目的:研究糖化血红蛋白与冠状动脉病变严重程度的相关性。方法:选取冠状动脉造影检查的病例256例,对照组58例,试验组198例,采用冠脉狭窄程度积分评价冠状动脉狭窄程度,检测糖化血红蛋白,分析糖化血红蛋白与冠状病变严重程度之间的关系。结果:试验组血清糖化血红蛋白水平均高于对照组,差异有统计学意义(P<0.05);冠状动脉病变支数与糖化血红蛋白值呈线性相关,差异有统计学意义(r=0.11,P=0.04);Gensini积分与糖化血红蛋白呈线性相关,差异有统计学意义(r=0.12,P=0.04)。结论:糖化血红蛋白水平与冠状病变积分显著相关,监测其水平可作为未行冠状动脉造影的疑似冠心病患者其病变严重程度的重要指标,有较高的预测价值。

Objective： To study the relationship between the severity of coronary artery disease and the severity of coronary artery disease.Method： Coronary angiography was used in 256 cases, 58 cases in the control group, 198 cases in the experimental group, the degree of coronary stenosis was used to evaluate the coronary artery stenosis degree, glycosylated hemoglobin was detected, the relationship of glyeosylated hemoglobin and the severity of coronary lesions was analyzed.Result： The experimental group serum glyeated hemoglobin level was significantly higher than that the control group, the difference was statistically significant （ P〈0.05 ） ; coronary lesion vessels and glycated hemoglobin values were linearly related, the difference was statistically significant （ r=0.11, P=0.04 ） ; Gensini score and glyeosylated hemoglobin showed a linear correlation, the difference was statistically significant （r=0.12, P=0.04 ） .Conclusion： Glycosylated hemoglobin level and coronary lesion score are significantly correlated, monitoring the level can be used as an important indicator of the severity of coronary artery disease in patients with coronary heart disease who no coronary angiography, it has a high predictive value.