TCD与低剂量双源性CTA对海南地区原居住居民后循环缺血及椎基底动脉易损斑块分布规律的研究

TCD and low-dose dual source of CTA of posterior circulation ischemia and vertebral basilar artery plaque regularity of distribution in original residents of Hainan area

目的探讨海南地区原住居民后循环血管缺血情况及椎基底易损斑块分布规律。方法 2015年1月—2015年8月期间对海南地区原住居民及内地迁居人群进行经颅多普勒(TCD)及低剂量双源CT血管造影(CTA)头颈血管筛查,共800例海南地区原住居民及500例内地迁居居民作为研究对象纳入研究。结果海南地区原住居民与内地迁居居民血管的狭窄部位多在椎基底动脉,经统计学检验发现二者血管狭窄部位构成有统计学差异(χ2=13.203,P=0.001)。海南地区原住居民L-VA、BA的Vs值,R-PCA、BA的Vm值,R-PCA、R-VA、BA的PI值均比内地迁居居民高,且具有统计学差异(Z=3.134,2.040,3.582,2.501,3.764,10.033,9.353,均P<0.05),R-VA的Vm值,R-PCA的Vd值比内地迁居居民低,且具有统计学差异(Z=4.092,3.126,P<0.05),未发现其它统计量具有统计学差异。海南地区原住居民椎基底动脉易损斑块检出率为47.38%,低于内地迁居居民椎基底动脉易损斑块检出率50.80%,未发现二者具有统计学差异(χ2=0.776,P>0.05)。海南地区原住居民R-VA存在易损斑块者比例低于内地迁居居民,且具有统计学差异(χ2=4.057,P=0.044),海南地区原住居民BA存在易损斑块者比例高于内地迁居居民,且具有统计学差异(χ2=10.149,P=0.001)。结论海南地区原住居民与内地迁居人群后循环血管缺血情况及椎基底易损斑块分布规律方面均有差异,本研究可以为人群制定相应预防措施奠定理论基础。

Objective To investigate the distribution of blood vessel ischemia and vulnerable plaque in the posterior circulation in Hainan.Methods During the period of January 2015 to August 2015,used TCD and low dose of dual source CT angiography of head and neck vascular screening Hainan Province indigenous residents and mainland settlers residents,a total of 800 cases of original inhabitants in Hainan area and 500 cases of mainland settlers residents as the objects were included in the study.Results The original inhabitants in Hainan area and the mainland settlers residents had vascular stenosis in basilar artery,the original inhabitants in Hainan area had higher L-VA,BA Vs,R-PCA,BA Vm,R-PCA、R-VA,BA PIthan the mainland settlers residents,and the difference was statistically significant（Z=3.134,2.040,3.582,2.501,3.764,10.033,9.353,P〈0.05）,had lower R-VA Vm,R-PCA Vd than the mainland settlers residents,and the difference was statistically significant（Z=4.092,3.126,P〈0.05）,there were no other statistics had statistically significant differences.The original inhabitants in Hainan area of vertebral basilar artery plaque detection rate for 47.38%,lower than the mainland settlers residents of vertebral basilar artery plaque detection rate was50.80%,there was no statistically significant differences（χ^2=0.776,P〈0.05）.R-VA vulnerable plaque in the original inhabitants in Hainan area was lower than that of the mainland settlers residents,and had statistically significant difference（χ^2=4.057,P=0.044）,BA vulnerable plaque in the original inhabitants in Hainan area was higher than the proportion of the mainland settlers residents,and the difference was statistically significant（χ^2=10.149,P=0.001）.Conclusion Original inhabitants in Hainan area and the mainland settlers residents after circulating vascular ischemia and vertebral basilar vulnerable plaque distribution were different.This study can help people formulate corresponding preventive measures to lay the theoretical foundation.