生物活性玻璃改性树脂粘接剂对牙本质脱矿及树脂粘接强度的影响

Effects of dentin demineralization and bond-strength properties of bioactive glass containing resin adhesive

目的研究生物活性玻璃(BG)改性树脂粘接剂抑制牙本质脱矿及对树脂-牙本质微拉伸粘接强度的影响。方法将硅烷偶联剂表面处理后的BG与Single Bond 2粘接剂混合制备出30%、40%和50%的BG改性的树脂粘接剂,选择上颌前磨牙40颗,随机分为4组,阴性对照组(不添加BG)、30%BG组、40%BG组、50%BG组,每组10颗。根据分组分别采用相应BG含量的粘接剂制备树脂-牙本质粘接试件。将制备的粘接试件在37℃水浴中浸泡24 h后进行微拉伸粘接强度测试。每组选择1个牙片浸泡在p H 4.0的人工唾液中1周,每24 h测试溶液的p H值。结果阴性对照组、30%BG组、40%BG组、50%BG组的粘接强度分别为(27.76±0.29)、(27.05±0.58)、(26.95±0.69)和(25.12±0.24)MPa。对照组和30%BG组的粘接强度无统计学差异(P=0.06),和40%BG组、50%BG组有统计学差异(P=0.04,P=0.00);30%、40%BG组的粘接强度高于50%BG组(P=0.00,P=0.00)。随着BG含量的增加,p H值也逐渐增高。结论含有BG的树脂粘接剂可以有效抑制牙本质的脱矿,30%BG组对短期的粘接强度无明显影响,50%BG组抑制脱矿能力最强,但是粘接强度较低。

ObjectiveThis study investigated the shear bond strength and the ability of resin adhesive containing different amounts of bioactive glass （BG） to prevent dentin demineralization.Methods BG bonds at 30%, 40%, and 50% concen-trations comprised a mixture of coupling agents modifying BG and Single Bond 2. Forty permanent premolars extracted for orthodontic treatment were randomly divided into four groups, namely, control group （BG-free）, 30% BG group, 40% BG group, and 50% BG group. Composite resin and dentin were prepared into bonding specimens by using respective adhesives and then immersed in artificial saliva at pH 4 for 1 week. Changes in the pH values of the solution were measured every 24 h. The microtensile bond strength （TBS） of each specimen was examined after immersion in distilled water at 37 ℃ for 24 h. Results The TBS values of the control group, 30% BG group, 40% BG group, and 50% BG group were （27.76±0.29）, （27.05± 0.58）, （26.95±0.69）, and （25.12±0.24） MPa, respectively. The TBS of the control group was not significantly different from that of the 30% BG group （P=0.06） but significantly higher than that of the 40% BG and 50% BG groups （P=0.04 andP=0.00, respectively）. In addition, TBS was significantly higher in the 30% BG and 40% BG groups than in the 50% BG group （P=0.00 andP=0.00, respectively）. The pH values of the solution increased with increasing BG content.Conclusion BG bonds are useful in the prevention of dentin demineralization. How-ever, in this study, the 30% BG group did not affect the short-term bond strength. The 50% BG group displayed the opti-mum ability to inhibit demineralization but showed the worst bond strength.