摘要
Establishment of genetic databases has socio-cultural, ethical and legal implications particularly in developing countries. However, there are no available data in Oman about the community knowledge and understanding of genetic database and gene banking. Thus, this study was conducted with the aim of investigating Omani public awareness on socio-cultural, ethical and legal aspects of gene studies （with consideration to regional variations） and to assess the public acceptance of initiating gene banking. This study was conducted using self-completed questionnaires by a sample of adult Omani population invited to participate in the study, from 14 health centers, a school and a university. For illiterate subjects, structured interviews were conducted. There were a total of 1,702 participants with nearly equal numbers of males and females. The mean age of respondents was 31 （＋ 12） years for males and 28 （＋ 10） years for females. In general, 9% of the studied population were illiterate and a total of 29% were preparatory school level and below, classified as the uneducated. While, 60% of the respondents were unemployed. The awareness on the genetic disposition of some common diseases was generally higher than 80% with the highest on sickle cell anemia. Only 17% of the participants had knowledge of genetic databases, 95% of whom were from the educated group. Public opinion on acceptance of gene banking, participation in genetic research and setting protection laws in those aware and non-aware, achieved good scores, indicating public acceptance of the above.
