重症肺炎支原体肺炎危险因素分析及临床意义

Risk factors and clinical significance of severe mycoplasma pneumoniae pneumonia

肺炎支原体肺炎在儿童中较为常见。近年来难治性肺炎支原体肺炎日趋增多，其中部分重症患儿虽经大环内酯类抗生素治疗仍难见效。然而糖皮质激素治疗有意想不到的效果。对重症肺炎支原体肺炎危险因素的识别，可能有助于早期予以激素干预，改善预后。临床研究发现，临床表现、影像学表现及实验室检查等多种指标与重症肺炎支原体肺炎的发生相关。该文对目前国内外研究所涉及的、可能与重症肺炎支原体肺炎发生相关的因素进行综述。

Mycoplasma pneumoniae pneumonias are common in children. In recent years, the incidence of refractory mycoplasma pneumonia has been increasing,and some of the severe children have a poor response to macrolide antibiotics. However,the effect of glucocorticoid therapy may have unexpected results. The recognition of severe mycoplasma pneumonia risk factors may contribute to intervent with glucocorticoid early, reduce the occurrence of severe mycoplasma pneumonia, and improve the prognosis. Clinical studies have found that clinical manifestations, imaging findings, laboratory tests and other factors are related to the occurrence of severe mycoplasma pneumonia. In this paper, the risk factors that may be associated with accurrence of severe mycoplasma pneumonias are reviewed.