摘要
Regulatory T cells (Tregs) comprise a subset of CD4+ T lymphocytes that holds promise as immunotherapy for inflammat- ory disease states including autoimmune disorders, solid organ allograft rejection, graft-versus-host disease, and acute inflam- matory conditions. However, limited availability of Treg numbers restricts their usefulness in cell transfer applications, particularly as patients may need multiple infusions for chronic diseases.
Regulatory T cells (Tregs) comprise a subset of CD4+ T lymphocytes that holds promise as immunotherapy for inflammat- ory disease states including autoimmune disorders, solid organ allograft rejection, graft-versus-host disease, and acute inflam- matory conditions. However, limited availability of Treg numbers restricts their usefulness in cell transfer applications, particularly as patients may need multiple infusions for chronic diseases.