安宫牛黄丸加减治疗重型颅脑损伤的效果观察

Effect observation of modified Angong Niuhuang Pill in the treatment of severe craniocerebral injury

目的 探讨安宫牛黄丸加减治疗重型颅脑损伤的效果。方法 收集本院2015年5月-2016年5月的重型颅脑损伤患者100例,随机将其分成两组,每组各50例,观察组患者采用安宫牛黄丸加减,对照组采用常规治疗,比较两组临床治疗效果及外周血清镁离子浓度的变化。结果 观察组患者治疗后显效率为90.00%,无效率为10.00%,对照组患者的显效率为80.00%,无效率为20.00%,两组比较差异有统计学意义（P〈0.05）;治疗后3、7、14 d时,观察组外周血清镁离子浓度明显高于对照组（P〈0.05）。结论 安宫牛黄丸加减治疗重型颅脑损伤具有明显效果,可显著改善患者预后,临床应用价值较高。

Objective To explore the effect of modified Angong Niuhuang Pill in the treatment of severe craniocerebral injury.Methods From May 2015 to May 2016,100 patients with severe craniocerebral injuries were collected in our hospital and evenly divided into two groups in random.In observation group,modified Angong Niuhuang Pill was used, while in control group,regular therapy was provided.The clinical therapeutic effect and change of the concentration of magnesium ion in peripheral blood were compared in both groups.Results The effectiveness rate after therapy in the observation group was 90.00%,the ineffectiveness rate after therapy in the observation group was 10.00%,while the rate in the control group was 80.00%,the ineffectiveness rate after therapy in the observation group was 20.00%,with a statistical difference （P〈0.05）.The concentration of magnesium ion in peripheral blood in the observation group was much higher than that in the control group 3,7,14 days after treatment （P〈0.05）.Condusion Modification of Angong Niuhuang Pill can obtain a great effect on treating severe cranioeerebral injury.It can remarkably improve patient＇s prognosis in a higher clinical application value.