HELLP综合征的治疗分析

Analysis on treatment of HELLP syndrome

目的探讨妊娠期高血压疾病并发两种类型HELLP综合征更有效的治疗方案。方法选择2010年1月-2015年1月唐山市妇幼保健院住院的HELLP综合征患者58例,分别探讨两种类型(完全型和部分型)HELLP综合征疾病诊断时、治疗7 d后孕妇(产妇)生化指标、硫酸镁用量、激素用量、血浆用量。结果疾病诊断时完全型较部分型HELLP综合征孕妇生化指标更为严重,但积极治疗7 d后二者孕妇的生化指标差异无统计学意义(P>0.05);治疗过程中完全型较部分型需要更多的激素与血浆,但硫酸镁用量无明显差异。结论妊娠期高血压疾病并发两种类型HELLP综合征终止妊娠后,解痉的同时积极使用激素及血浆有助于疾病的预后。

Objective To explore the more effective treatment for hypertensive disorder complicating pregnancy （HDCP） combined with two types of HELLP syndrome. Methods Fifty-eight HELLP syndrome patients were selected from the hospital from January 2010 to January 2015. The biochemical indicators, magnesium sulfate doses, hormones doses, and plasma doses during diagnosis and after seven days of treatment were analyzed respectively in patients with two types of HELLP syndrome （ complete type and partial type） . Results The biochemical indicators of pregnant women with complete HELLP syndrome during diagnosis were more severer than those of pregnant women with partial HELLP syndrome, but after seven days of treatment, there was no statistically significant difference （P〉0. 05） ; compared with pregnant women with partial HELLP syndrome, the pregnant women with complete HELLP syndrome needed more hormone and plasma in the course of treatment, but there was no significant difference in magnesium sulfate dose. Conclusion After termination of pregnancy among the patients with HDCP combined with two types of HELLP syndrome, spasmolysis combined with applications of hormone and plasma is helpful to prognosis.