摘要
微透析技术是一项可以连续监测某物质在特定组织器官中代谢水平的技术,利用该技术对移植肝进行一系列物质监测,尤其是葡萄糖、乳酸、甘油、丙酮酸及部分氨基酸的监测。通过这些物质的变化,对移植术后移植肝的并发症及缺血再灌注损伤作提前预知。本文主要综述了微透析技术的原理、特点及其在监测肝移植术后机体并发症及移植过程中缺血再灌注损伤的应用,并指出当前该技术所遇到的主要问题以及未来研究的趋势,以期为该领域的进一步研究提供参考。
Objective Microdialysis technique is a technology which can continuous monitoring of a substance′s metabolism level in specific tissues or organs,it can provide a series of substances monitoring of the liver transplantation,especially monitoring of glucose,lactate,glycerol,pyruvate and some amino acids. By the range of these substances, we can anticipate complications and ischemia?reperfusion injury after liver transplantation. In this paper we reviewed the principle, characteristics of the microdialysis technique and its applications of monitoring the ischemia?reperfusion and complications after liver transplantation,then pointed out the main problems and trends of the technology to provide a reference for further research in the field.
出处
《中国综合临床》
2016年第7期667-669,共3页
Clinical Medicine of China
关键词
微透析
肝移植
缺血再灌注
Microdialysis
Liver transplantation
Ischemia-reperfusion