胆总管结石高龄患者行内镜逆行胰胆管造影治疗的安全性和有效性探讨

Safety and efficacy of endoscopic retrograde cholangiopancreatography in elderly patients with choledocholithiasis

目的：通过比较不同年龄段患者内镜逆行胰胆管造影（ ERCP）的应用情况，分析和探讨ERCP在高龄患者中应用的有效性和安全性。方法选取2012年1月至2015年1月，石河子大学医学院第一附属医院进行胆总管结石ERCP患者360例，按年龄分组，其中≥75岁患者120例，60～75岁患者123例，≤60岁患者117例。记录患者ERCP操作及并发症情况，对结果进行统计分析。结果360例患者进行了377次ERCP，操作成功率及并发症发生率差异无统计学意义（ P＞0．05）；结论胆总管结石高龄组患者进行ERCP操作能够取得和非高龄组一样的疗效，ERCP在各年龄段的操作是安全有效的。

Objective To compare the application of endoscopic retrograde cholangiopancreatography （ ERCP ） in the patients at different ages in order to explore the safety and efficacy of the approach in the elderly .Methods A total of 360 patients undergoing ERCP in our hospital between January 2012 and January 2015 were collected and retrospectively studied .They were divided into very old group （≥75 years old, n=120）, old group （60-75 years old, n=123）, and the non-elderly group （≤60 years old, n=117）. Their operation conditions and complications were investigated and compared among the 3 groups.Results There were overall 377 ERCP procedures performed in the 360 cases.There were no significant differences in the success rate of ERCP procedure and incidence of complications among the 3 groups （P〉0.05）.Conclusion Diagnostic and therapeutic ERCP exerts similar efficacy in the elderly as in the non-elderly patients .ERCP is safe and effective in the patients at different ages .