贵州省2012～2015年无偿献血者血液筛查不合格情况分析

Analysis of Blood Screening Disqualification of Voluntary Blood Donors in Guizhou Province From 2012 to 2015

目的：通过比较分析2012～2015年贵州省血站血液筛查ALT、HBsAg、抗-HCV、抗-HIV和抗-TP共5项指标的不合格情况，了解贵州省献血人群的输血相关传染性疾病感染情况，进行统计学分析，探讨相关应对措施。方法采集贵州省血站血液检测实验室2012～2015年血液标本ALT、HBsAg、抗-HCV、抗-HIV、抗-TP检测不合格情况，进行回顾性统计分析。结果贵州省2012～2015年血液检测不合格率为4.42%，5项指标不合格率ALT＞抗-TP＞HBsAg＞抗-HCV ＞抗-HIV，分别为：2.20%、0.95%、0.80%、0.27%、0.21%。年度不合格率逐年下降，各年度间不合格率差异有统计学意义。结论采取积极措施加强献血知识宣传，做好献血前健康征询和献血前筛查工作，防止高危人群献血，选择合适的检测策略，减少技术因素造成的假阳性，做好假阳性献血者的回归，从而保证血液安全，保障血液供应。

Objective To compare the results of screening disqualification of ALT,HBsAg,anti-HCV,anti-HIV,anti-TP from 2012 to 2015 with the aim of investigating blood transfusion related infectious diseases in Guizhou blood donors,performing the statistical analysis and exploring relevant the countermeasures to enhance the blood safety.MethodsThe disqualification of blood screening results of ALT,HBsAg,anti-HCV,anti-HIV,anti-TP were collected and retrospective statistical analysis were subsequently performed from 2012 to 2015.Results The total disqualification rate was 4.42% in Guizhou Province from 2012 to 2015 and the positive rates of ALT,anti-TP,HBsAg,anti-HCV, anti-HIV were 2.20%,0.95%,0.80%,0.27%,0.21%.The disqualification rates were descent by year with statistical significance.Conclusion Blood donation knowledge and boold donation health consultation should be evolved. The donation of high-risk population should be banned and appropriate testing strategies should be chosen to decrease the false positive and make the calling of false positive blood donors,which aims in enhancing blood safety and blood supply.