甲氨蝶呤联合米非司酮治疗异位妊娠临床疗效及安全性

Clinical Efficacy and Safety of Methotrexate Combined With Mifepristone in the Treatment of Ectopic Pregnancy

目的分析甲氨蝶呤联合米非司酮治疗异位妊娠临床疗效及安全性。方法选取我院收治的异位妊娠患者46例,采用甲氨蝶呤治疗为常规组,采用甲氨蝶呤联合米非司酮治疗为试验组,各23例,对两组患者的治疗效果进行比较。结果试验组患者治疗有效率及β-HCG恢复时间短于常规组(P<0.05)。结论异位妊娠患者采用甲氨蝶呤联合米非司酮治疗后不良反应少,效果良好。

Objective To analyze the clinical efficacy and safety of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods Selected were treated in our hospital from ectopic pregnancy in 46 patients, treated with methotrexate as routine group, using mifepristone combined with methotrexate therapy as experimental group, 23 cases in each. The treatment effect of two groups of patients were compared. Results The effective rate of treatment and recovery time of beta -HCG were shorter in the experimental group than in the conventional group （P〈0.05）. Conclusion The patients with ectopic pregnancy were treated with methotrexate combined with mifepristone, the adverse reaction was less, and the effect was good.