肝硬化上消化道出血患者经奥美拉唑联合奥曲肽治疗的临床研究

Clinical Study on Patients With Omeprazole Combined With Octreotide in the Treatment of Cirrhosis With Upper Gastrointestinal Bleeding

目的 对肝硬化上消化道出血患者经奥美拉唑联合奥曲肽治疗进行临床研究。方法 选取我院2010年10月-2015年10月收治的肝硬化上消化道出血患者128例,随机分为对照组和观察组,对照组使用奥美拉唑进行治疗,观察组使用奥美拉唑联合奥曲肽治疗,对比分析两组患者止血时间和治疗效果。结果 观察组止血时间和治疗效果均优于对照组,差异具有统计学意义（P〈0.05）,观察组治疗总有效率为96.88%,对照组治疗总有效率为65.62%。结论 奥美拉唑联合奥曲肽能够有效治疗肝硬化上消化道出血患者。

Objective For patients treated by omeprazole combined with octreotide in clinical study of cirrhosis with upper gastrointestinal bleeding. Methods Liver cirrhosis were selected in our hospital from October 2010 to October 2015, 128 patients of hemorrhage of upper digestive tract, and randomly assigned to control group and the observation group, the control group used omeprazole treatment, the observation group used omeprazole combined with octreotide in the treatment of, comparative analysis of two groups of patients stop bleeding time and treatment effect. Results Observation group hemostasis time and treatment effect were better than the control group, the difference was statistically significant （P〈0.05）, the total effective rate of observation group was 96.88%, and the control group was 65.62%. Conclusion Omeprazole combined with octreotide can effectively treat patients with gastrointestinal bleeding in liver cirrhosis digestive.