八角莲中一个新双黄酮

A new biflavone from Dysosma versipellis

本文对八角莲进行了化学成分研究。采用硅胶、反相硅胶RP-C18及凝胶LH-20柱色谱等方法分离八角莲中的化学成分,应用IR、MS、NMR、2D-NMR等方法进行结构分析。从八角莲95%乙醇提取物中分离鉴定了10个化合物：dysoverine D（1）、dysoverine F（2）、dysoverine A（3）、podoverine A（4）、α-足叶草脂素（5）、芦丁（6）、山柰酚-3-O-β-D-吡喃葡萄糖苷（7）、槲皮素-3-O-β-D-吡喃葡萄糖苷（8）、山柰酚（9）及槲皮素（10）。化合物2为新化合物,化合物1、3~6均为首次从该植物中分离得到。

This study was conducted to investigate the chemical constituents in the root of Dysosma versipellis（Hance） M. Cheng. The constituents were isolated by silica gel, lichroprep RP-C18 and pharmadex LH-20 column chromatography and the IR, MS, NMR, 2D-NMR spectroscopic analysis were employed for the structural elucidation. Ten compounds were isolated from the 95% ethanol extract of Dysosma versipellis, their structures were elucidated as dysoverine D（1）, dysoverine F（2）, dysoverine A（3）, podoverine A（4）, α-peltatin（5）, rutin（6）, kaempferol-3-O-β-D-glucopyranoside（7）, quercetin-3-O-β-D-glucopyranoside（8）, kaempferol（9） and quercetin（10）. Compound 2 is a new compound, and compounds 1 and 3-6 were isolated from this plant for the first time.