在对患者进行胸部多层螺旋CT增强扫描时用不同速率注射对比剂的效果研究

Study on the pharmacokinetics of the contrast agent in the CT enhancement scanning of the chest

目的探讨在对患者进行胸部多层螺旋CT增强扫描时用不同速率注射对比剂的效果。方法将近年来在我院进行胸部多层螺旋CT增强扫描的78例受检者根据注射对比剂速率的不同(分别为3.0m L/s、4.0m L/s、5.0m L/s)分为A组、B组与C组,分别检测其主动脉的强化峰值及到达峰值的时间、肺动脉干的强化峰值及到达峰值的时间、主动脉及肺动脉的Tb200等指标。结果 C组患者在进行多层螺旋CT增强扫描时其Tb200最短,但为其注射对比剂的速率(5m L/s)过快,会使其心脏承受较大的负担,而且其强化CT值维持在200Hu以上的时间偏短。A组患者在进行多层螺旋CT增强扫描时其强化CT值大多在200HU以下。与A组患者相比,B组患者在进行多层螺旋CT增强扫描时其强化峰值较高,其强化CT值维持在200Hu以上的时间较长,其Tb200较短,差异有统计学意义(P<0.05)。结论与采用3.0m L/s、5.0m L/s的速率注射对比剂相比,在对患者进行多层螺旋CT增强扫描时采用4.0m L/s的速率为其注射对比剂的成像效果最优。

Objective To investigate the pharmacokinetics of in the chest blood vessels by using multi slice spiral CT. Methods 78 patients who were randomly divided into 4 groups, 5.0mL/s, Tb200, three, B, C and A. Results in the three groups, the peak of pulmonary artery trunk, the time and the time of aortic enhancement, Tb200 showed significant difference （P〈0.05）. The peak value of pulmonary arterial enhancement was significantly higher than that of the aorta （P〈0.05）, . Conclusion the peak time of the contrast agent was increased, and the peak time was earlier than that of the pulmonary artery.