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系统性红斑狼疮合并化脓性关节炎六例临床分析

Septic arthritis in systemic lupus erythematosus: a retrospective analysis of 6 cases
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摘要 本研究通过总结分析系统性红斑狼疮(SLE)合并化脓性关节炎的临床特征,发现在起病时SLE疾病活动指数高、WBC减少、累计糖皮质激素用量高及进行甲泼尼龙冲击、关节腔穿刺与化脓性关节炎发生密切相关.临床上SLE患者一旦怀疑化脓性关节炎,应及时行关节液检查、培养,并给予敏感抗菌药物治疗,必要时请外科协助行关节腔清理并置管冲洗。 Base on the clinical characteristics of septic arthritis in a group of systemic lupus erythematosus patients,this study has found out that high systemic lupus erythematosus disease activity index,leucopenia,high cumulative dose of glucocorticoid,methylprednisolone intravenous pulse therapy and joint cavity puncture were closely correlated with septic arthritis.Once septic arthritis is suspected,culture specimens should be collected and appropriate antibiotics are suggested immediately.Also,surgical drainage is a very useful approach.
出处 《中华内科杂志》 CAS CSCD 北大核心 2016年第8期631-633,共3页 Chinese Journal of Internal Medicine
关键词 红斑狼疮 系统性 关节炎 感染性 Lupus erythematosus,systemic Arthritis,infection
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参考文献4

  • 1Huang JL, Hung J J, Wu KC, et al. Septic arthritis in patients with systemic lupus erythematosus: salmonella and nonsalmonella infections compared [ J ]. Semin Arthritis Rheum, 2006,36 ( 1 ) : 61-67.
  • 2Gupta MN, Sturrock RD, Field M. A prospective 2-year study of 75 patients with adult-onset septic arthritis [ J]. Rheumatology ( Oxford), 2001,40( 1 ) :24-30.
  • 3Gerona JG, Navarra SV. Salmonella infections in patients with systemic lupus erythematosus: a case series [ J ]. Int J Rheum Dis, 2009, 12 (4) : 319-323.
  • 4Suh CH, Jeong YS, Park HC, et al. Risk factors for infection and role of C-reactive protein in Korean patients with systemic lupus erythematosus [ J ]. Clin Exp Rheumatol, 2001,19 ( 2 ) : 191-194.

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