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巴多昔芬对子宫内膜异位症模型大鼠异位内膜组织中ERα、ERβ、AP-1、VEGF表达的影响 被引量:3

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摘要 子宫内膜异位症(内异症)是雌激素依赖性疾病,严重影响育龄期妇女的生命质量及生育能力。关于其发病机制, Sampson最先提出“经血逆流学说”,近年的“在位内膜决定论”认为,内异症的在位内膜与非子宫内膜异位症存在本质上的不同,其分子生物学行为可能源于雌激素暴露,雌激素作用于ER,启动对应的信号通路,多条信号通路相互作用的结果促进了逆流的子宫内膜能在宫腔以外生长。
出处 《中华妇产科杂志》 CAS CSCD 北大核心 2016年第7期541-543,共3页 Chinese Journal of Obstetrics and Gynecology
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参考文献14

  • 1仝佳丽,郎景和,朱兰,冯瑞娥,崔全才.内异症患者在位内膜病理特征分析[J].中华妇产科杂志,2012,47(11):829-832. 被引量:8
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二级参考文献25

  • 1杨萍,纳冬荃,熊亚龙,李云,孙德敏,祁昆,杨云娟.大鼠子宫内膜异位模型的建立与组织学观察[J].中国实验动物学报,2006,14(2):139-141. 被引量:25
  • 2子宫内膜异位症的诊断与治疗规范[J].中华妇产科杂志,2007,42(9):645-648. 被引量:565
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