摘要
The glucose mass transfer in the biosynthesis of succinic acid with immobilized Actinobacillus succinogenes cells has been comparatively analyzed for a bioreactor with mobile bed vs. a stationary basket bioreactor. The process has been considered to occur under substrate and product inhibitory effects. The results indicated that the bioreactor with mobile bed is more efficient for biocatalyst particles with a diameter over 3 mm, while the basket bioreactor is more efficient for smaller biocatalyst particles and basket bed thickness below 5 mm. The performances of both configurations of immobilized A. succinogenes cell beds were found to be superior to the column packed bed bioreactor.
The glucose mass transfer in the biosynthesis of succinic acid with immobilized Actinobacillus succinogenes cells has been comparatively analyzed for a bioreactor with mobile bed vs. a stationary basket bioreactor. The process has been considered to occur under substrate and product inhibitory effects, The results indicated that the biore- actor with mobile bed is more efficient for biocatalyst particles with a diameter over 3 mm, while the basket bio- reactor is more efficient for smaller biocatalyst particles and basket bed thickness below 5 mm, The performances of both configurations of immobilized A. succinogenes cell beds were found to be superior to the column packed bed bioreactor.
基金
Supported by the Grant PN-II-PT-PCCA-2011-3.1-1268 authorized by The National Council for Scientific Research-Executive Unit for Financing Higher Education,Research,Development and Innovation(CNCS-UEFISCDI)
