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化生性乳腺癌的研究进展 被引量：1

Advanced research on metaplastic breast carcinoma
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摘要 化生性乳腺癌(MBC)是一种少见的恶性肿瘤,肿瘤体积一般较大、生长速度快,但很少发生腋窝淋巴结转移。MBC的组织类型复杂且病理分型多样,诊断主要依靠病理学检查。目前国内外尚无明确治疗指南。大部分MBC患者雌激素受体(ER)、孕激素受体(PR)和人类表皮生长因子受体2(Her-2)呈阴性,故内分泌治疗和分子靶向治疗不敏感。手术治疗效果确切,保乳术加前哨淋巴结活检术为首选术式。积极推荐放疗,化疗可作为辅助治疗手段,治疗效果和预后均较浸润性乳腺癌(IDC)差。本文作者从MBC的临床诊断、综合治疗和影响预后因素等方面进行综述。
作者 洪景辉 付彤 赵刚 贾泓瑶 刘瑞东 宋东
机构地区 吉林大学第一医院乳腺外科
出处 《吉林大学学报（医学版）》 CAS CSCD 北大核心 2016年第4期839-842,共4页 Journal of Jilin University：Medicine Edition
基金 吉林省科技厅科技发展计划项目资助课题(20120736)
关键词 乳腺肿瘤 化生性乳腺癌 浸润性乳腺癌 免疫组织化学
分类号 R737.9 [医药卫生—肿瘤]
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参考文献38

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二级参考文献25

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吉林大学学报（医学版）
2016年 第4期

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