Pathogenicity of the Homoplasmic m.8701A〉 G Variant Requires Confirmation
Pathogenicity of the Homoplasmic m.8701A〉 G Variant Requires Confirmation
摘要
To the Editor： We read with interest the article by Zhu et al. about a family with dilated cardiomyopathy （dCMP） and arterial hypertension （AHT） in four members being attributed to the m.8701A〉G variant in the ATP6 gene. We have the following comments and concerns.
To the Editor： We read with interest the article by Zhu et al. about a family with dilated cardiomyopathy （dCMP） and arterial hypertension （AHT） in four members being attributed to the m.8701A〉G variant in the ATP6 gene. We have the following comments and concerns.
二级参考文献35
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1Murtuza B, Fenton M, Burch M, Gupta A, Muthialu N, Elliott MJ, et al. Pediatric heart transplantation for congenital and restrictive cardiomyopathy. Ann Thorac Surg 2013;95:1675-84. doi: 10.1016/j. athoracsur.2013.01.014.
-
2Zheng X, Chen S, Wang J, Yang T, Chen Y. Dilated cardiomyopathy with hypertension: Prevalence and response to high-dose B l-adrenoceptor antagonist therapy. Clin Exp Pharmacol Physiol 2009;36:945-9. doi: 10.1 II IIj .1440-1681.2009 .05184.x.
-
3Chan SH, WuKL, ChangAY, Tai MH, Chan N. Oxidative impairment of mitochondrial electron transport chain complexes inrostral ventrolateral medulla contributes to neurogenic hypertension. Hypertension 2009;53:217-27. doi: I0.1161IHYPERTENSIONAHA.108.116905.
-
4Armani C, Botto N, Andreassi MG, Centaro E. Molecular markers of cardiovascular damage in hypertension. Curr Pharm Des 2013;19:2341-50.
-
5Li R, Liu Y, Li Z, Yang L, Wang S, Guan MX. Failures in mitochondrial tRNAMet and tRNAGln metabolism caused by the novel 440IA>G mutation are involved in essential hypertension in a Han Chinese family. Hypertension 2009;54:329-37. doi: 10.1161IHYPERTENSIONAHA.109.129270.
-
6Liu Y, Li R, Li Z, Wang XJ, Yang L, Wang S, et al. Mitochondrial transfer RNAMet 4435A>G mutation is associated with maternally inherited hypertension in a Chinese pedigree. Hypertension 2009;53:1083-90. doi: 10.1161IHYPERTENSIONAHA.109.128702.
-
7Li Z, Liu Y, Yang L, Wang S, Guan MX. Maternally inherited hypertension is associated with the mitochondrial tRNA (lie) A4295G mutation in a Chinese family. Biochem Biophys Res Commun 2008;367 :906-11. doi: 10.10 16/j .bbrc.2007 .12.150.
-
8Wang S, Li R, Fettermann A, Li Z, Qian Y, Liu Y, et al. Maternally inherited essential hypertension is associated with the novel 4263A>G mutation in the mitochondrial tRNAlle gene in a large Han Chinese family. Circ Res 2011;108:862-70. doi: 10.116I1CIRCRESAHA.110.231811.
-
9McNally EM, Golbus JR, Puckelwartz MJ. Genetic mutations and mechanisms in dilated cardiomyopathy. J Clin Invest 20 13; 123: 19-26. doi: 10.1172/JCI62862.
-
10Bhasin P, Kapoor S. Impact of consanguinity on cardio-metabolic health and other diseases: Findings from an Afro-Indian tribal community. J Community Genet 2015;6:129-35. doi: 10.1007/s12687-014-0207-z.
-
1海涛.不可轻视的心肌病[J].今日科苑,2012(6):99-99.
-
2周嫒媛（编译）.研究认为酒精具有免疫调节作用[J].科学新闻,2008(18):6-6.
-
3特种氧化铝的应用领域及市场现状[J].阻燃材料与技术,2005(1):23-23.
-
4Monika Budnik Radoslaw Piatkowski Janusz Kochanowski Renata Glowczynska Dariusz Gorko Robert Kowalik Arkadiusz Pietrasik Grzegorz Opolski.The oldest patient with takotsubo cardiomyopathy[J].Journal of Geriatric Cardiology,2015,12(5):588-589. 被引量：1
-
5陈松,杜垲.吸收式热泵初步分析与研究[J].制冷技术,2003,23(3):12-16. 被引量：7
-
6Betul Erer,Zekeriya Nurkalem,Ahmet Lutfu Orhan,Duygu Ersan Demirci,Memduh Dursun,Mehmet Eren.Isolated biventricular noncompaction： a case report[J].Chinese Medical Journal,2010(7):969-971.
-
7NOMI Adnan,宋秉春,张金国,尉希清.Research progress on noncompaction of ventricular myocardium[J].South China Journal of Cardiology,2017,18(1):79-86.
-
8苏蕊,张新胜,陈驰.乙二醛电氧化合成乙醛酸产物的分离[J].化工学报,2010,61(S1):43-50. 被引量：1
-
9Ye Zhu,Xiang Gu,Chao Xu.A Mitochondrial DNA A8701G Mutation Partly Associated with Maternally Inherited Hypertension and Dilated Cardiomyopathy in a Chinese Pedigree[J].Chinese Medical Journal,2016(15):1890-1890.
-
10Guangyong Huang,Hang Gao,Xiangang Meng,Zhonghua Yan,Xiangquan Kong,Lexin Wang.Related factors of dilated cardiomyopathy[J].Journal of Geriatric Cardiology,2009,6(2):87-90.
