摘要
The regioselective allylic alkylation of 1,2-dihydroquinolines and Morita-Baylis-Hillman（MBH） adducts has been developed. By surveying various reaction parameters, we summarized the effects of temperatures, relative reactant doses, catalysts, solvents and N-protected groups on the regioselectivity of this transformation. This method provides a facile protocol for the preparation of allylic a-substituted dihydroquinolines.
The regioselective allylic alkylation of 1,2-dihydroquinolines and Morita-Baylis-Hillman（MBH） adducts has been developed. By surveying various reaction parameters, we summarized the effects of temperatures, relative reactant doses, catalysts, solvents and N-protected groups on the regioselectivity of this transformation. This method provides a facile protocol for the preparation of allylic a-substituted dihydroquinolines.
