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糖尿病微血管内皮细胞功能受损机制研究进展 被引量:22

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摘要 糖尿病是我国最常见的代谢性疾病之一,其发病机制主要包括胰岛β细胞进行性功能衰竭和胰岛素抵抗。近年研究表明微循环功能异常可能也参与了糖尿病的发病机制[1-2]。微血管内皮细胞作为机体微循环的主要组成成分,其功能受损直接参与了糖尿病及其并发症的发生发展。笔者针对微血管内皮细胞及其功能、与靶器官靶组织的关系、糖尿病微血管内皮细胞损伤的代谢和分子机制、相关治疗药物等领域中的研究进展进行综述。
出处 《中华糖尿病杂志》 CAS CSCD 2016年第7期439-442,共4页 CHINESE JOURNAL OF DIABETES MELLITUS
基金 基金项目:协和青年基金和中央高校基本科研业务费专项资金(33320140193,3332015200)
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