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钠-葡萄糖共转运蛋白2抑制剂的肾脏效应 被引量:1

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摘要 钠-葡萄糖共转运蛋白2(sodium-glucose co-transporter2, SGLT-2)抑制剂(SGLT-2i)是一种新型的口服降糖药物,该类药物通过抑制肾脏近曲小管葡萄糖重吸收,促进尿糖排泄而降低血糖。此类药物的靶器官为肾脏,因此其肾脏安全性备受关注。本文综述了SGLT-2i研发以来的临床研究证据,阐述SGLT-2i治疗的肾脏安全性及其潜在的肾脏保护作用。
出处 《中华糖尿病杂志》 CAS CSCD 2016年第7期445-446,共2页 CHINESE JOURNAL OF DIABETES MELLITUS
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