2型糖尿病合并睡眠呼吸暂停低通气综合征患者骨代谢的变化被引量：1

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摘要选择苏州大学附属第三医院2012年2月至2016年1月内分泌科住院行多导睡眠(PSG)监测的男性T_2DM患者共118例,其中合并OSAHS的T_2DM患者组(TO组)58例为病例组,未合并OSAHS的T_2DM患者组(DM组)60例作为对照组,分别检测血糖等,采用多导睡眠图(PSG)监测睡眠呼吸暂停指数(AHI)。结果 TO组体重指数(BMI)、腰围、臀围、收缩压、舒张压、空腹C肽、三酰甘油、尿酸值显著高于DM组,差异有统计学意义(P<0.05)。TO组的骨密度显著低于DM组,而血清P1NP及β-CTX水平均显著高于DM组(P<0.05)。T_2DM合并OSAHS患者的血清P1NP及β-CTX水平与呼吸暂停低通气指数(AHI)均呈显著正相关,相关指数分别为(0.432,0.469,P<0.05)。结论 T_2DM合并OSAHS患者血压及尿酸水平升高,糖脂代谢紊乱更严重,且骨转换率增加,骨量下降。

作者钱凤娟王龙华飞唐暎杨洁蒋晓红

机构地区湖北省孝感市中心医院内分泌

出处《实用糖尿病杂志》 2016年第3期39-42,共4页 Journal of Practical Diabetology

关键词 2型糖尿病阻塞性睡眠呼吸暂停低通气综合征骨代谢标志物骨密度

分类号 R587.1 [医药卫生—内分泌] R766 [医药卫生—耳鼻咽喉科]

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