摘要
肛周派杰氏病(perianal Paget's disease,PPD)是一种少见的上皮内腺癌,临床表现不典型,极易误诊.诊断主要靠病理检查发现病变组织中有派杰特细胞.本文报道肛管直肠管状-绒毛状腺瘤伴可疑PPD 1例,经肛门局部行扩大切除术,术后经病检确诊为PPD.为进一步提高和增强临床医师对罕见病的认识及诊治水平,本文通过复习文献详细讨论了PPD的组织发生、临床特点、病理特征、诊断、鉴别诊断、治疗及预后.
Perianal Paget＇s disease（PPD） is a kind of rareintraepithelial carcinoma that is easily misdiagnosed due to atypical clinical manifestations.The diagnosis of PPD relies mainly on pathological examination by recognizing the presence of Paget＇s cells.Here we report a case of anorectal tubularvillous adenocarcinoma with PPD,which was confirmed by immunohistochemical method after extended local excision via the anus.In order to enhance clinicians＇ awareness of this rare disease and improve its diagnosis and treatment,we performed a literature review to discuss the histogenesis,clinical features,pathological characteristics,diagnosis,differential diagnosis,treatment and prognosis of PPD.
出处
《世界华人消化杂志》
CAS
2016年第20期3215-3218,共4页
World Chinese Journal of Digestology
关键词
肛周派杰氏病
诊断
外科治疗
Perianal Paget＇s disease
Diagnosis
Surgical treatment
