急性非ST段抬高型心肌梗死PCI治疗疗效分析

Analysis on effects of PCI for treating acute non ST segment elevation myocardial infarction

目的分析比较经皮冠状动脉内介入(PCI)治疗与药物保守治疗对急性非ST段抬高型心肌梗死(NSTEMI)患者的疗效。方法选取2012年1月至2014年12月在该院就诊的NSTEMI患者156例。根据患者及其家属意愿分别采用PCI治疗(PCI治疗组,103例)和药物保守治疗(保守治疗组,53例)。分析比较两组患者入院时及出院后1、6个月心功能相关指标,以及随访期间主要不良心脏事件(MACE)的发生情况。结果 PCI治疗组1、6个月时氨基末端脑利钠肽前体(NT-pro BNP)、左心室舒张末内径均明显低于保守治疗组,左心室射血分数明显高于保守治疗组,而MACE发生率也明显低于保守治疗组,差异均有统计学意义(P<0.05)。结论 PCI治疗能明显改善NSTEMI患者在中、短期内的心功能,减少MACE的发生,疗效明显优于药物保守治疗。

Objective To analyze and compare the effects of percutaneous coronary intervention （PCI） and medication conservative therapy in treating the patients with acute non-ST segment elevation myocardial infarction（NSTEMI）. Methods A to-tal of 156 patients with NSTEMI in our hospital from January 2012 to December 2014 were selected and respectively adopted PCI treatment（PCI treatment group,103 cases） and medication conservative treatment（conservative treatment group,53 cases）. The cardiac function related indicators before admission and at 1,6 months after admission in the two groups were analyzed,and the occurrence situation of major adverse cardiac events（MACE） during the follow-up period were concluded. Results The NT-proB-NP and left ventricular end diastolic diameter at 1 ,6 months in the PCI treatment group were significantly lower than those in the conservative treatment group,while left ventricular ejection fraction was significantly higher than that in the conservative treatment group and the incidence rate of MACE was significantly lower than that in the conservative treatment group ,the differences were statistically significant（P〈0.05）. Conclusion The PCI therapy can obviously improve the meddle-short term heart function in the patients with acute NSTEMI,reduces the occurrence of MACE,the effect is significantly superior to that of the medication conser-vative therapy.