The complex contribution of the astrocyte scar
The complex contribution of the astrocyte scar
摘要
It is tempting to assign positive or negative roles to components of neurotrauma pathology,in an effort to generate an ordered picture and design therapeutic strategies accordingly.However nature is seldom so obliging.This principle is elegantly illustrated in a recent publication from Anderson,
It is tempting to assign positive or negative roles to components of neurotrauma pathology,in an effort to generate an ordered picture and design therapeutic strategies accordingly.However nature is seldom so obliging.This principle is elegantly illustrated in a recent publication from Anderson,
参考文献10
-
1Anderson MA, Burda JE, Ren Y, Ao Y, O'Shea TM, Kawaguchi R, Coppola G, Khakh BS, Deming TJ, Sofroniew MV (2016) Astrocyte scar formation aids central nervous system axon regeneration. Nature 532:195-200.
-
2Huang DW, McKerracher L, Braun PE, David S (1999) A therapeutic vaccine approach to stimulate axon regeneration in the adult mammalian spinal cord. Neuron 24:639-647.
-
3Liddelow SA, Barres BA (2016) Regeneration: Not everything is scary about a glial scar. Nature 532:182-183.
-
4Liuzzi FJ, Lasek RJ (1987) Astrocytes block axonal regeneration in mammals by activating the physiological stop pathway. Science 237:642-645.
-
5Morganti JM, Riparip LK, Rosi S (2016) Call off the Dog(ma): M1/ M2 polarization is concurrent following traumatic brain injury. PLoS One 11:e0148001.
-
6Neumann S, Woolf CJ (1999) Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury. Neuron 23:83-91.
-
7Piantino J, Burdick JA, Goldberg D, Langer R, Benowitz LI (2006) An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury. Exp Neuro1201:359-367.
-
8Schwab ME, Thoenen H (1985) Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J Neurosci 5:2415-2423.
-
9Silver J, Miller JH (2004) Regeneration beyond the glial scar. Nat Rev Neurosci 5:146-156.
-
10Silver J, Schwab ME, Popovich PG (2015) Central nervous system regenerative failure: role of oligodendrocytes, astrocytes, and microglia. Cold Spring Harb Perspect Biol 7:a020602.
-
1付饶.秦文彩:从抗战老兵到对日合作[J].中国石油石化,2015,0(23):75-78.
-
2李海如,吴蕾,华春清,张涛,唐梦霓.改良兰氏法合并腭帆提肌重建修复腭裂的临床研究[J].中国继续医学教育,2013,5(1):11-13. 被引量:1
-
3Athanasios Saratzis SaifMohamed.Endovascular abdominal aortic aneurysm repair in the geriatric population[J].Journal of Geriatric Cardiology,2012,9(3):285-291.
-
4伍文彬,赖先荣,索朗其美,孟宪丽.藏药多血康对家兔血瘀症模型全血黏度及红细胞流变性的影响[J].西藏科技,2009(2):39-40. 被引量:6
-
5王恩彤,赵敏.Regulation of tissue repair and regeneration by electric fields[J].Chinese Journal of Traumatology,2010,13(1):55-61. 被引量:4
-
6Wang Haiyan,Xue Yusheng,Zheng Qiangsun,Liu Yin,Tang Yanling,Wang Yi,Zhang Luxing,JiaZhixin,Huang Jianbo.A portable,economic drainage device to prevent pocket hematoma of pacemakers[J].Journal of Medical Colleges of PLA(China),2009,24(3):167-175.