探究胺碘酮治疗充血性心力衰竭合并室性心率失常的临床价值

Clinical value of amiodarone in treatment of congestive heart failure complicated by ventricular arrhythmia

目的探究胺碘酮治疗充血性心力衰竭(CHF)合并室性心率失常的临床价值。方法选择104例CHF并室性心率失常者,将其平分为研究组与对照组。对照组积极采取抗心衰治疗方案,研究组在此基础上应用胺碘酮治疗。结果研究组抗心率失常与心功能的有效率为90.38%、90.38%,均高于对照组的75.00%、73.08%(P<0.05)。两组不良反应对比差异无统计学意义(P>0.05)。结论胺碘酮可以强化CHF并室性心率失常患者的心功能状态,控制心律失常,安全可靠,适于临床应用。

Objective To investigate the clinical value of amiodarone in the treatment of congestive heart failure（CHF） complicated by ventricular arrhythmia. Methods A total of 104 CHF patients with ventricular arrhythmia were enrolled and equally divided into research group and control group. The patients in the control group were actively treated by cardiotonic treatment regimen, and those in the research group were given amiodarone in addition to the cardiotonic treatment regimen. Results The research group had significantly higher response rates in the treatment of arrhythmia and restoration of normal cardiac function than the control group（90.38% /90.38% vs 75.00% /73.08%, P〈0.05）. The adverse events showed no significant difference between the two groups（P〉0.05）. Conclusion Amiodarone can enhance cardiac function and control arrhythmia in CHF patients with ventricular arrhythmia and is safe and reliable in clinical practice.