早期进展性脑梗死的危险因素分析

Risk factors for early progressive cerebral infarction

目的分析早期进展性脑梗死(EPCI)的危险因素。方法采用回顾性研究的方法,对48例EPCI患者(EPCI组)及86例非进展性脑梗死患者(ACI组)的一般临床因素、脑梗死相关因素进行对比分析,然后将上述两组差异有统计学意义的指标进行二分类logistic多因素回归分析。结果两组血纤维蛋白原水平及高血压、糖尿病、脑微出血例数相比,P均<0.05;糖尿病、脑微出血与脑梗死的进展密切相关(P均<0.05)。结论糖尿病及脑微出血是EPCI的独立危险因素。

Objective To investigate the risk factors for the early progressive cerebral infarction（ EPCI）. Methods The general clinical factors and cerebral infarction related factors were compared between 48 cases of EPCI patients（ EPCI group） and 86 cases of non-progressive cerebral infarction patients（ ACI group） by using retrospective analysis. Subsequently,the statistically significant indicators from above univariate analysis were analyzed using binary logistic regression analysis. Results Fibrinogen,hypertension,diabetes and cerebral microbleeds were significantly different between these two groups（ all P 0. 05）. Cerebral microbleeds and diabetes were closely related to the progressive cerebral infarction（ all P 0. 05）. Conclusion Cerebral microbleeds and diabetes were the independent risk factors for EPCI.