老年高血压患者颈动脉内膜中层厚度与血清同型半胱氨酸、胱抑素C的相关性被引量：3

Association of intima-media thickness of common carotid artery with serum homocysteine,cystatin C and creatinine in elderly hypertensive patients.

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摘要目的探讨老年高血压患者颈动脉内膜中层厚度(IMT)与血清同型半胱氨酸(Hcy)、胱抑素C(Cys-C)等的关系。方法测定80例(IMT增厚组)及77例(IMT正常组)老年高血压患者空腹静脉血Hcy、Cys-C、肌酐、尿酸等水平。结果 IMT增厚组Hcy为(24.0±8.3)μmol/L、Cys-C(2.4±0.7)pg/ml、肌酐(104.0±31.1)μmol/L、尿酸(356.8±110.8)μmol/L;均显著高于IMT正常对照组。血清Hcy水平与肌酐、尿素氮、尿酸呈显著的正相关;Hcy、Cys-C是影响老年高血压患者颈动脉IMT增厚的危险因素。结论联合检测血清Hcy、Cys-C水平有助于评价老年高血压患者大血管动脉粥样硬化的进展程度。 Objective To explore the relationship between serum homocysteine（Hcy）, cystatin C（Cys-C）, and etc. in elderly hypertensive patients.Methods The serum levels of Hcy,Cys-C,creatinine and uric acid were detected in 80 subjects with increased IMT（group A） and 77 cases of normal IMT （group C）.Results Serum Hcy was（24.0±8. 3）/μmol/L,Cys-C was（2.4±0. 7）pg/ml,creatinine was（104.0±31.1）μmol/L and uric acid was （356.8±110.8）μmol/L in group A, which were significantly higher than those in group C. Serum level of Hcy and Cys-C was positively correlated with creatinine and uric acid. Hcy and Cys-C was the risk factors for the increase of IMT in elderly hypertensive patients. Conclusion Combined examination of Hcy and Cys-C is helpful to evaluate the progress of macrovascular atherosclerosis in elderly hypertensive patients.

作者李刚

机构地区马鞍山市中心医院干部病房

出处《中国冶金工业医学杂志》 2016年第4期376-378,共3页 Chinese Medical Journal of Metallurgical industry

关键词同型半胱氨酸胱抑素C 肌酐尿酸颈动脉内膜中层厚度老年高血压 Homocysteine Cystatin C Creatinine Intima-media thickness Elderly hypertensive

分类号 R544.1 [医药卫生—心血管疾病]

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