磷酸奥司他韦颗粒治疗流感样肺炎的疗效观察

Efficacy of oseltamivir phosphate granules treatment of flu-like pneumonia

目的磷酸奥司他韦颗粒治疗流感样肺炎的疗效观察。方法将发热流感样病毒性肺炎患儿264例随机分为观察组和对照组各132例。两组均使用常规治疗。观察组在此基础上给予磷酸奥司他韦颗粒治疗,每日按公斤体重分2次给药,口服5 d为一疗程;对比两组效果。结果观察组退热时间,咳嗽消退时间,头疼、肌肉酸痛缓解时间,肺部啰音减少或消失时间均优于对照组。差异有统计学意义(P<0.05),观察组总有效率95.9%明显优于对照组67.8%。差异有统计学意义(P<0.05)。结论奥司他韦颗粒治疗流感样肺炎效果明显,值得推广应用。

Objective To observe the neuraminidase inhibitors（ oseltamivir granules） and the efficacy of treatment of pneumonia flu-like fever. Methods 264 cases of flu-like fever virus pneumonia were randomly divided into observation group and the control group with each of 132 cases. Both groups were using conventional therapy. Observation group was given on the basis of oseltamivir phosphate granules treatment,body weight in kilograms divided twice daily,orally 5 days for treatment; compared two groups of effects. Results The time of fever,cough subsided time,headache,muscle pain relief time,pulmonary rales decreased or disappeared time than the control group. Differences exist statistically significant（ P〈0. 05）,the total effective observation group than the control group 95. 9% 67. 8%. Differences were statistically significant（ P〈0. 05）. Conclusions Oseltamivir treatment of influenza-like particles pneumonia effect is obvious,should be widely applied.