不同生长年限白芍中主要成分含量的比较研究

Comparison of the contents of major ingredients in Radix paeoniae alba with different growth phases

目的 ：比较不同生长年限的白芍中主要成分含量,为白芍规范化种植、采收提供科学依据。方法 ：采用HPLC法测定白芍中没食子酸、氧化芍药苷、芍药内酯苷、芍药苷、苯甲酸与1,2,3,4,6-五没食子酰葡萄糖含量。结果 ：随着生长年限的增加,没食子酸和苯甲酸含量逐年下降,而芍药苷、氧化芍药苷、芍药内酯苷和1,2,3,4,6-五没食子酰葡萄糖含量却逐渐增加。结论 ：4~5年生的白芍有效成分含量最高,适宜采收。

Objective： To compare the contents of major ingredients in Radix paeoniae alba with different growth phases. Methods： The contents of gallic acid, oxypaeoniflorin, albiflorin, peoniflorin, benzoic acid and 1,2,3,4,6-pentagalloylglucose from Radix paeoniae alba with 2~ 5 years of growth phases were determined by HPLC so as to provide a scientific evidence for the planting and harvest of Radix paeoniae alba. Results： The contents of gallic acid and benzoic acid were gradually decreased while the contents of oxypaeoniflorin, albiflorin, peoniflorin and 1,2,3,4,6-pentagalloylglucose increased with the increase of its growth phase. Conclusion： The contents of active ingredients in Radix paeoniae alba with 4~5 years of growth phase are the highest, suggesting it is the most suitable time for harvest.