控制性低中心静脉压的研究进展

The Study Progress of Controlled Low Central Venous Pressure

肝癌、肝硬化及肝内胆管结石是我国常见的肝脏疾病,其较为有效的治疗方法均为肝叶切除术。然而肝脏解剖复杂、血供丰富,术中易导致大出血。控制性低中心静脉压(LCVP)可显著减少肝脏手术的出血量,并且不影响机体肝肾功能及氧供需平衡,但目前尚无统一的标准。最近发现低中心静脉压不但不能减少肝脏手术患者术中的出血量,也不能降低患者术后病死率以及提高术后长期生存率。

Hepatocellular caminoma, liver cirrhosis,and calculus of intrahepatic duct are the most common liver diseases in China,the most effective treatment of which is hepatic resection. But because the anatomy of the liver is complex and the blood supply are abundance, the hepatic resection may cause hemorrhea. Controlled low central venous pressure（LCVP） can significantly reduce the blood loss in the hepatic resection, and has little side reaction on the liver function and renal function and the oxygen supply of the system, though there is no unified standard yet. Some recent studies reported that LCVP could neither reduce the mortality after the hcpatectomy nor increase the long survival rate, even couldn＇t reduce the blood loss.