小儿热性惊厥复发的相关因素分析

Related Factors Affecting Recurrence of Infantile Febrile Convulsion

目的研究小儿热性惊厥复发的影响因素及其预防措施。方法回顾性分析2009年3月至2012年3月佛山市南海区第四人民医院儿科收治的290例小儿热性惊厥首发患儿的临床资料，应用单因素分析复发情况的影响因素，分析热性惊厥患儿复发的影响因素。结果首次发作患儿160例，复发患儿130例，热性惊厥患儿复发的影响因素单因素分析显示，剖宫产、女性、复杂热性惊厥、有直系亲属发病史、首次发作年龄为6个月至2岁、首次发病体温〈39．5℃的患儿复发率高于顺产、男性、单纯热性惊厥、无直系亲属发病史、首次发作年龄为2～6岁、首次发病体温≥39．5℃的患儿[50．6％（79／156）比19．4％（26／134）、44．4％（59／133）比29．3％（46／157）、34．2％（83／155）比16．3％（22／135）、51．3％（80／156）比18．6％（25／134）、48．7％（74／152）比22．5％（31／138）、47．8％（76／159）比22．1％（29／131）]，差异有统计学意义（P〈0．05）。分娩方式、惊厥首次发作类型、直系亲属发病史、患儿首次发作年龄以及首次发作体温是患儿复发的影响因素（P〈0．05）。结论了解热性惊厥的复发影响因素，有助于筛查小儿热性惊厥重点对象。

Objective To investigate the related factors affecting recurrence of infantile febrile seizures and its preventive measures. Methods The clinical data of 290 children with febrile convulsion in Foshan City Nanhai District Fourth People＇s Hospital between Mar. 2009 and Mar. 2012 were retrospectively analyzed. The univariate analysis was used to analyze the effect of different factors on the recurrence. Results There were 160 cases of first onset and 130 cases of recurrence. Univariate analysis showed that the relapse rates of children with Cesarean section, female, thermal complex convulsions, withimmediate family history of the disease, first onsetduring 6 months and 2 years old, the first onset temperature 〈 39.5 ℃ were higher than children with eutocia, male, simple febrile seizures, no immediate family history of the disease, the first attack during 2 and 6 years old,the first onset temperature≥39.5 ℃ [50. 6% （79/156） vs 19.4% （26/ 134） ,44. 4% （59/133） vs 29. 3% （46/157） ,34.2% （83 /155 ） vs 16.3% （22/135） ,51.3% （80/156） vs 18.6% （25/134） ,48.7% （74/152） vs 22.5% （31/138） ,47. 8% （76/159） vs 22. 1% （29/131） ], the differences were statistically significant（ P 〈 0. 05 ）. Mode of delivery, first convulsion seizure type, immediate family history of disease, age, children age of the first episode, temperature of the first episode were factors influencing the recurrence in children （ P 〈 0. 05 ）. Conclusion Knowing factors influencing the recurrence of the febrile convulsion is helpful to screen the primary objects of infantile febrile convulsion.