摘要
目的研究雷贝拉唑治疗老年性返流性食管炎的临床疗效。方法选取我院2012年1月~2014年1月84例老年性反流性食管炎患者为研究对象,运用随机数表法随机分组为观察组和对照组,每组为42例。对照组采用常规治疗;观察组在常规治疗的基础上服用雷贝拉唑。比较两组临床疗效及胃内PH值变化。结果两组治疗后总有效率分别为85.7%、76.2%,两组比较无统计学意义（P〉0.05）;对照组起效时间为（112.35±103.25）min高于观察组（70.83±25.36）min,两组比较有统计学意义（P〈0.05）。治疗前两组胃内PH值比较无统计学意义（P〉0.05）;治疗后观察组胃内PH值高于对照组,两组相比有统计学意义（P〈0.05）。结论雷贝拉唑治疗老年性反流性食管炎效果较好,可快速发挥抑酸作用,值得临床应用和推广。
Objective： To investigate the clinical efficacy of rabeprazole in treating senile reflux esophagitis.Methods： Totally, 84 elderly patients with reflux esophagitis in our hospital from January 2012 to January 2014 were selected as the objects of study. They were randomly divided into test group and control group with 42 patients in each group. Both groups were given the routine treatment, while the patients in test group received additional treatment with rabeprazole, compared with clinical efficacy and intragastric PH in the two groups.Results： The total effective rate of treatment in two groups had no significant difference（P〈0.05）（85.7% vs. 76.2%）.The onset time in control group [（112.35±103.25） min] was significantly higher than those in test group [（70.83±25.36） min]（P〈0.05）. After treatment, intragastric PH in test group was significantly higher than those in control group（P〈0.05）, although it was no statistical significance in both groups before treatment（P〈0.05）.Conclusions： The rabeprazole has a good result for treating senile reflux esophagitis, it can exert acid suppression more quickly, worth to be spread and clinical application.
出处
《西藏医药》
2016年第3期41-43,共3页
Tibetan Medicine
