高脂血症性急性胰腺炎患者的临床特征(28例)

Clinical Characteristics of 28 Cases with Hyperlipidemic Acute Pancreatitis

目的分析并总结高脂血症性急性胰腺炎(HLAP)患者的临床特征,以提高对该病的临床诊治水平。方法选取2014年7月至2016年1月收治的28例HLAP患者作为观察组,并随机选取30例胆源性胰腺炎(BAP)患者作为对照组,对病史资料进行回顾性分析。结果观察组平均年龄、血清淀粉酶水平、C-反应性蛋白(CRP)水平低于对照组,而体重指数(BMI)、血三酰甘油及胆固醇水平、合并糖尿病及脂肪肝比率及复发率高于对照组,差异均有统计学意义(P<0.05)。16例轻症HLAP患者的三酰甘油水平及胆固醇水平分别为(13.93±1.42)mmol/L、(7.86±1.44)mmol/L,12例重症HLAP患者的三酰甘油水平及胆固醇水平分别为(18.04±1.38)mmol/L、(11.05±1.15)mmol/L。结论与BAP相比,HLAP的发病年龄低,血清淀粉酶及CRP升高不显著,但合并糖尿病、脂肪肝者较多,且更易复发。HLAP病情轻重与血脂水平呈正相关。

Objective The clinical characteristics of hyperlipidemic acute pancreatitis （HLAP） were analyzed and summarized, in order to improve the diagnostic and therapeutic performance of this disease. Methods 28 cases of patients with HLAP from July 2014 to January 2016 were selected into the observation group, 30 cases of patients with BAP were selected into the control group, the clinical data were retrospectively analyzed. Results The overage age, serum levels of amylase and CRP of observation group were lower than that of control group. Compared to control group, the BMI, serum levels of blood triglyceride and cholesterol, the ratio of complicated with diabetes and folly liver disease, recurrence rote were higher. The difference was statistically significant （ p〈0.05 ） . The serum levels of blood triglyceride and cholesterol of the 16 mild HEAP cases were （13.93±1.42） mmol/L, （7.86± 1.44） mmol/L and that of the 12 severe cases were （18.04± 1.38） mmol/L, （11.05 ±1.15） mmol/L. Conclusion Compared to BAP, HLAP has its own characteristics： o younger age incidence, lower serum levels of amylase and CRP, most of them are complicated with diabetes or falty liver, and recurrence rate is much higher. There is a positive correlation between serum lipids and HEAP.