丝素/聚己内酯纳米纤维膜结构与力学性能的研究

Structure and Mechanical Properties of Silk Fibroin/Poly(ε-caprolactone) Nanofiber Membranes

利用高压静电纺丝技术制备丝素(SF)/聚己内酯(PCL)纳米复合纤维膜。通过热场发射扫描电镜、傅里叶红外光谱、广角X-射线衍射和力学拉伸的方法表征了纳米纤维膜的结构与力学性能。结果表明:随着纺丝液浓度的提高,纤维直径增大,在电纺液浓度为20%时,纳米纤维网中纤维形态清晰、直径分布较均匀、成膜性较好;随着溶质中丝素含量的降低,纳米纤维膜的力学拉伸性能由硬而脆向软而弱转变,在SF含量达到50%时,纤维膜的力学性能已得到较好改善;甲醇可诱导SF的分子构象从无规卷曲和SilkⅠ转变为SilkⅡ;纳米纤维膜中纤维呈无规则排列,双轴力学拉伸表现为各向同性。

In this article, silk fibroin （SF）/poly（ε-caprolactone）（PCL） nanocomposite fiber membranes were prepared by using high-voltage electrostatic spinning technology, and the structure and mechanical properties of the nanofiber membranes were characterized by using FE-SEM, ATR-FTIR, XRD and mechanical stretching methods. The results showed that the diameters of fibers increase with increase of the concentration of spinning solution and the fibers in the nanofiber membranes have clear morphology, evenly distributed diameters and excellent film-forming performance when the solution concentration reaches 20%; the mechanical tensile properties of the nanofiber membranes turn from hard and brittle to soft and weak when the SF content in the solution reduces; methanol can induce the SF molecular conformation to turn from randomly crimped and Silk Ⅰ to Silk Ⅱ; and the fibers in the nanofiber membranes are randomly an-anged and present isotropic biaxial mechanical tensile.