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重组白细胞介素2纯化方法的建立

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摘要 目的本文建立了重组人白细胞介素2(r IL-2)的纯化方法。方法依次利用CM Sepharose FF捕获、SOURCE 30 RPC纯化、CM Sepharose FF浓缩和凝胶过滤法分离重组白细胞介素2。结果通过SDS-PAGE电泳和HPLC-PRC检测,表明纯化后的r IL-2纯度较高。结论建立了r IL-2的纯化方法,该纯化方法简单,稳定,纯化效果好,可为r IL-2的生产工艺提供技术支持和依据。
作者 陈志华
出处 《海峡药学》 2016年第7期261-263,共3页 Strait Pharmaceutical Journal
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