1B Keren,S C Arnold.Blood coagulation factor Xa as an emerging drug target[J].Expert Opinion on Therapeutic Targets,2011,15(3):341-349.
2M Nigel,RE Tilley,NS Key.Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis[J].Arteriosclerosis Thrombosis&Vascular Biology,2007,27(8):1687-1693.
3Q Lu,L Yang,C Manithody,X Wang,et al.Molecular basis of the clotting defect in a bleeding patient missing the Asp-185 codon in the factor X gene[J].Thrombosis Research,2014,134(5):1103-1109.
4S Rana,L Yang,SM Hassanian,AR Rezaie.Determinants of the specificity of protease-activated receptors 1 and 2 signaling by factor Xa and thrombin[J].Journal of Cellular Biochemistry,2012,113(3):977-984.
5M Marzia,V Anna,P Roberta,M Giuseppe,C Luigi,et al.A recurrent Gly43Asp substitution in coagulation Factor X rigidifies its catalytic pocket and impairs catalytic activity and intracellular trafficking[J].Thrombosis Research,2013,133(3):481-487.
6J Xing,L Yang,H Li,Q Li,L Zhao,et al.Identification of anthranilamide derivatives as potential factor Xa inhibitors:Drug design,synthesis and biological evaluation[J].European Journal of Medicinal Chemistry,2015,95:388-399.
7FS Markland,S Swenson.Snake venom metalloproteinases[J].Toxicon Official Journal of the International Society on Toxinology,2013,62(62):3-18.
8M Suntravat,I Nuchprayoon,JC Pérez.Comparative study of anticoagulant and procoagulant properties of 28 snake venoms from families Elapidae,Viperidae,and purified Russell’s viper venom-factor X activator(RVV-X)[J].Toxicon:Journal of the International Society on Toxinology,2010,56(4):544-553.
9RJ Jenny,KG Mann,RL Lundblad.A critical review of the methods for cleavage of fusion proteins with thrombin and factor Xa[J].Protein Expression&Purification,2003,31(1):1-11.